Argentina
• Los Glaciares
• Jesuit Missions of the Guaranis: San Ignacio Mini, Santa Ana, Nuestra Señora de Loreto and Santa Maria Mayor (Argentina), Ruins of Sao Miguel das Missoes (Brazil)
• Iguazu National Park
• Cueva de las Manos, Río Pinturas
• Península Valdés
• Ischigualasto / Talampaya Natural Parks
• Jesuit Block and Estancias of Córdoba
• Quebrada de Humahuaca

Belize
• Belize Barrier Reef Reserve System

Bolivia
• City of Potosí
• Jesuit Missions of the Chiquitos
• Historic City of Sucre
• Fuerte de Samaipata
• Noel Kempff Mercado National Park
• Tiwanaku: Spiritual and Political Centre of the Tiwanaku Culture

Brazil
• Historic Town of Ouro Preto
• Historic Centre of the Town of Olinda
• Jesuit Missions of the Guaranis: San Ignacio Mini, Santa Ana, Nuestra Señora de Loreto and Santa Maria Mayor (Argentina), Ruins of Sao Miguel das Missoes (Brazil)
• Historic Centre of Salvador de Bahia
• Sanctuary of Bom Jesus do Congonhas
• Iguaçu National Park
• Brasilia
• Serra da Capivara National Park
• Historic Centre of São Luís
• Atlantic Forest South-East Reserves
• Discovery Coast Atlantic Forest Reserves
• Historic Centre of the Town of Diamantina
• Central Amazon Conservation Complex
• Pantanal Conservation Area
• Brazilian Atlantic Islands: Fernando de Noronha and Atol das Rocas Reserves
• Cerrado Protected Areas: Chapada dos Veadeiros and Emas National Parks
• Historic Centre of the Town of Goiás

Chile
• Rapa Nui National Park
• Churches of Chiloé
• Historic Quarter of the Seaport City of Valparaíso
• Humberstone and Santa Laura Saltpeter Works
• Sewell Mining Town

Colombia
• Port, Fortresses and Group of Monuments, Cartagena
• Los Katíos National Park
• Historic Centre of Santa Cruz de Mompox
• National Archeological Park of Tierradentro
• San Agustín Archeological Park
• Malpelo Fauna and Flora Sanctuary

Costa Rica
• Talamanca Range-La Amistad Reserves / La Amistad National Park
• Cocos Island National Park
• Area de Conservación Guanacaste

Cuba
• Old Havana and its Fortifications
• Trinidad and the Valley de los Ingenios
• San Pedro de la Roca Castle, Santiago de Cuba
• Desembarco del Granma National Park
• Viñales Valley
• Archaeological Landscape of the First Coffee Plantations in the South-East of Cuba
• Alejandro de Humboldt National Park
• Urban Historic Centre of Cienfuegos

Dominica
• Morne Trois Pitons National Park

Dominican Republic
• Colonial City of Santo Domingo

Ecuador
• City of Quito
• Galápagos Islands
• Sangay National Park
• Historic Centre of Santa Ana de los Ríos de Cuenca

El Salvador
• Joya de Ceren Archaeological Site

Guatemala
• Antigua Guatemala
• Tikal National Park
• Archaeological Park and Ruins of Quirigua

Haiti
• National History Park – Citadel, Sans Souci, Ramiers

Honduras
• Maya Site of Copan
• Río Plátano Biosphere Reserve

Mexico
• Historic Centre of Mexico City and Xochimilco
• Historic Centre of Oaxaca and Archaeological Site of Monte Albán
• Historic Centre of Puebla
• Pre-Hispanic City and National Park of Palenque
• Pre-Hispanic City of Teotihuacan
• Sian Ka'an
• Historic Town of Guanajuato and Adjacent Mines
• Pre-Hispanic City of Chichen-Itza
• Historic Centre of Morelia
• El Tajin, Pre-Hispanic City
• Historic Centre of Zacatecas
• Rock Paintings of the Sierra de San Francisco
• Whale Sanctuary of El Vizcaino
• Earliest 16th-Century Monasteries on the Slopes of Popocatepetl
• Historic Monuments Zone of Querétaro
• Pre-Hispanic Town of Uxmal
• Hospicio Cabañas, Guadalajara
• Archeological Zone of Paquimé, Casas Grandes
• Historic Monuments Zone of Tlacotalpan
• Archaeological Monuments Zone of Xochicalco
• Historic Fortified Town of Campeche
• Ancient Maya City of Calakmul, Campeche
• Franciscan Missions in the Sierra Gorda of Querétaro
• Luis Barragán House and Studio
• Islands and Protected Areas of the Gulf of California
• Agave Landscape and Ancient Industrial Facilities of Tequila
• Central University City Campus of the Universidad Nacional Autónoma de México (UNAM)

Nicaragua
• Ruins of León Viejo

Panama
• Fortifications on the Caribbean Side of Panama: Portobelo-San Lorenzo
• Darien National Park
• Talamanca Range-La Amistad Reserves / La Amistad National Park
• Archaeological Site of Panamá Viejo and Historic District of Panamá
• Coiba National Park and its Special Zone of Marine Protection

Paraguay
• Jesuit Missions of La Santísima Trinidad de Paraná and Jesús de Tavarangue

Peru
• City of Cuzco
• Historic Sanctuary of Machu Picchu
• Chavin (Archaeological Site)
• Huascarán National Park
• Chan Chan Archaeological Zone
• Manú National Park
• Historic Centre of Lima
• Río Abiseo National Park
• Lines and Geoglyphs of Nasca and Pampas de Jumana
• Historical Centre of the City of Arequipa

Saint Kitts and Nevis
• Brimstone Hill Fortress National Park

Saint Lucia
• Pitons Management Area

Suriname
• Central Suriname Nature Reserve
• Historic Inner City of Paramaribo

Uruguay
• Historic Quarter of the City of Colonia del Sacramento

Venezuela (Bolivarian Republic of)
• Coro and its Port
• Canaima National Park
• Ciudad Universitaria de Caracas